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Efficacy and Safety of Cannabinoid Oromucosal Spray for Multiple Sclerosis Spasticity
Abstract
Background: The approval of 9-δ-tetrahydocannabinol and cannabidiol (THC:CBD) oromucosal spray (Sativex) for the management of treatment-resistant multiple sclerosis (MS) spasticity opened a new opportunity for many patients...
The Effectiveness of Injectable Extended-Release Naltrexone vs Daily Buprenorphine-Naloxone for Opioid Dependence
Key Points
Question: Are monthly intramuscular injections with extended-release naltrexone hydrochloride as effective as daily oral buprenorphine–naloxone hydrochloride in reducing the use of heroin and other illicit substances in newly...
Unmet Treatment Needs for People with Mental Health and Substance Use Disorders
In the US, less than 10% of adults with co-occurring mental health problems and substance use disorders get treatment for both. 50% do not receive treatment for either.
This highlights the vast discrepancy between the prevalence of co...
The Brain Under Construction – A Window into the Developing Brain
The Brain Under Construction – A Window into the Developing Brain is a new debriefing paper by Mentor-Adepis. It forms part of a mini-series on the ‘Brain Under Construction’, which is geared towards helping professionals to better...
School-Based Alcohol and Drug Education and Prevention – What Works?
School-Based Alcohol and Drug Education and Prevention – What Works? is a new briefing paper published by Mentor-Adepis. It outlines several approaches that have been shown to work effectively, and issues cautions about those that have not...
Social Media in the Classroom: An Experiential Teaching Strategy to Engage and Educate
Abstract
This article outlines an approach to engaging and educating college students through the use of social media. The project is designed for a substance use course at the college/university undergraduate level. However, it could be...
‘My GP says I drink too much’: Screening and Brief Intervention
In the absence of greater obstacles to availability, widespread screening to identify and then briefly advise risky drinkers has been the great hope for improved alcohol-related public health. This major hot topic update guides you through...
Financial Incentives to Discontinue Long-Term Benzodiazepine Use
Abstract
Objectives: Investigate the acceptability of financial incentives for initiating a medically supervised benzodiazepine discontinuation programme among people with long-term benzodiazepine use and to identify programme features...
8 Steps Towards Minimising the US Opioid Crisis
Current levels of opioid addiction in the US are so alarming that in July 2017 the President’s Commission on Combating Drug Addiction and the Opioid Crisis urgently suggested that President Trump declare a national emergency to free up...
Drug and Alcohol Treatment Statistics
Executive Summary
Data collected in drug treatment agencies play a prominent role in informing policy makers. Such data often represent the only information collected regularly and consistently over a certain period of time. What is even...
Effectiveness Bank Drug Treatment Matrix Cell C1: Life and Death Decisions for Drug Harm Reduction Management
Explores how harm reduction impacts are affected by the management of the service and of the intervention. Highlights the studies which showed that treatment-termination and needle-exchange policies can mean life or death for service users...
Brief Intervention to Promote Smoking Cessation and Improve Glycemic Control in Smokers with Type 2 Diabetes
Abstract
The aim of the study was to examine the effects of a brief stage-matched smoking cessation intervention group compared with a control group (with usual care) in type 2 diabetes mellitus patients who smoked by randomized...
Effectiveness of Optional Videoconferencing-Based Treatment of Alcohol Use Disorders
ABSTRACT
Background: Treatment of alcohol use disorders (AUDs) is characterized by an adherence rate below 50%. Clinical research has found that patient adherence enhances treatment effect; hence, health authorities, clinicians, and...
Transcranial Magnetic Stimulation of Dorsolateral Prefrontal Cortex Reduces Cocaine Use
Abstract
Recent animal studies demonstrate that compulsive cocaine seeking strongly reduces prelimbic frontal cortex activity, while optogenetic stimulation of this brain area significantly inhibits compulsive cocaine seeking, providing...
Efficacy and Safety of High-Dose Baclofen for the Treatment of Alcohol Dependence
Abstract
Previous randomised placebo-controlled trials with low-to-medium doses of baclofen (30–60 mg) showed inconsistent results, but case studies suggested a dose-response effect and positive outcomes in patients on high doses of...
Lack of Sleep and Substance Use: A Worrying Link
Children and adolescents need more sleep than adults. A good night's sleep for those in their teens is considered to be 8.5 – 9.5 hours. Just over ¼ of US high school students get 8+ hours of sleep a night, according to the 2015 Youth Risk...
Barriers and Facilitators to Implementing Addiction Medicine Fellowships
Abstract
Background
Although progress in science has driven advances in addiction medicine, this subject has not been adequately taught to medical trainees and physicians. As a result, there has been poor integration of evidence-based...
Effectiveness Bank Drug Treatment Matrix Cell B1: The Practitioner in Harm Reduction
Second cell of the Drug Treatment Matrix explores key studies on the impact of the practitioner on reducing harms associated with illegal drug use, in which trust emerges as a fundamental ingredient. Reconceptualise needle exchanges as safe...
Multimorbidity in Patients Enrolled in a Community-Based Methadone Maintenance Treatment Programme Delivered through Primary Care
Abstract
Background: Multimorbidity, the co-existence of two or more (2+) long-term conditions in an individual, is common among problem drug abusers.
Objective: To delineate the patterns, multimorbidity prevalence, and disease...
A Socioecological Approach to Addressing Tobacco-Related Health Disparities
Tobacco use remains the nation’s leading cause of preventable premature death, including death from cancer, and progress in reducing tobacco use and related disease and death has not been equally distributed across population groups. This...
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