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In the 99th edition of the CIJ Informa magazine, you can find a selection of news on the activities carried out by Centros de Integración Juvenil (CIJ), the host institution of the ISSUP Mexico National Chapter.

On this occasion, the...

Abstract

Objective

The crisis of opioid use puts a strain on resources in the United States and worldwide. There are 3 US Food and Drug Administration–approved medications for treatment of opioid use disorder: methadone, buprenorphine...

Abstract

Microglia participates in the modulation of pain signaling. The activation of microglia is suggested to play an important role in affective disorders that are related to a dysfunction of the mesocorticolimbic system (MCLS) and...

Abstract

Background

Alcohol use disorders (AUD) are prevalent and often go untreated. Patients are commonly screened for AUD in primary care, but existing treatment programs are failing to meet demand. Digital therapeutics include...

Opioid dependence is associated with substantial health and social burdens, and opioid agonist treatment (OAT) is highly effective in improving multiple outcomes for people who receive this treatment. Methadone and buprenorphine are common...

Key Points

Question  What treatments for cocaine use disorder are associated with objective reductions in cocaine use among adults?

Findings  In this meta-analysis of 157 clinical trials comprising 402 treatment groups and 15 842...

Overview

Cocaine is the hydrochloride salt produced from the leaves of the coca plant. Powder cocaine is typically snorted and less frequently injected. Crack is a smokable form of cocaine and is manufactured from cocaine hydrochloride.

الكوكايين هو عقار منشط يسبب الإدمان ينشأ من أوراق نبات الكوكا ، وهو موطنه الأصلي في أمريكا الجنوبية. تشمل تأثيرات الدواء زيادة اليقظة والانتباه والطاقة ، فضلا عن مشاعر النشوة والثقة. ومع ذلك ، فإن هذه الآثار تأتي بتكلفة عالية ، لأن تعاطي...

Introduction

The markets for hexahydrocannabinol (HHC) and related semi-synthetic cannabinoids (SSC) are rapidly evolving areas with relatively limited information currently available.

The European situation presented in Section 1 can...

Objective: To better understand current developments in the treatment of stimulant use.

Background: Stimulant drugs are second only to cannabis as the most widely used class of illicit drug globally, accounting for 68 million past...

Abstract

Introduction

Young adults report high rates of current cannabis use. The increase of legalised cannabis in the United States has led to greater access and availability, causing cannabis to become the new “gateway” drug. This...

It has been widely reported that youth alcohol consumption has decreased over recent years. What is the evidence to support this view? What are the implications for alcohol related health harm, promotion of safe drinking and health policy?

There has been substantial progress in the discussion and implementation of decriminalisation of drugs in the past 10 years. The issue is more broadly discussed and is more central to wider discourse around drug use and drug harms...