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The DIMS annual report 2022 covers the concentrations, adulterations, and other relevant information produced by DIMS in the past year, and in doing so forms a topical image of the Dutch drug market. Spread out over all Dutch provinces, the...

Harm reduction (HR) has been a pillar of drug policy in the Netherlands for many decades. In fact, the Netherlands was a pioneer in the field of HR. Like many other Western countries, the Netherlands was hit by a wave of heroin use in the...

Abstract

Background

Microglia have been implicated in the pathophysiology of major depressive disorder (MDD), but information on biological mechanisms is limited. Therefore, we investigated the gene expression profile of microglial cells...

Abstract

While it has been suggested that cocaine use and relapse in women is more strongly related to stress-relief craving, whereas cocaine use in men is more strongly related to reward craving, the neural mechanisms that underlie these...

Abstract

Patients with attention-deficit/hyperactivity disorder (ADHD) often develop early onset substance use disorder (SUD) and show poor treatment outcomes. Both disorders show similar reward-processing alterations, but it is unclear...

The lockdowns that have been introduced around the world in response to the COVID-19 pandemic have dramatically influenced health behaviours.

This research, published in Drug and Alcohol Dependence explores the impact of lockdown on...

Abstract

Background

The use of illicit substances is correlated, meaning that individuals who use one illicit substance are more likely to also use another illicit substance. This association could (partly) be explained by overlapping...

Abstract

Background

Little research has investigated in-depth how physicians perceive their role in smoking cessation care. This qualitative study sought to understand physicians’ perceptions of responsibility for smoking cessation.

Meth

Abstraktní

Východiska: Ibogain je látka, která byla vyhodnocena jako neschválená antinávyková látka pro léčbu drogové závislosti. Náhlá srdeční smrt byla popsána jako sekundární k jeho použití. Popisujeme klinické účinky a toxikokinetiku...

Abstract

This meta-analysis demonstrates that the video feedback method has a statistically significant effect on the interaction skills of professionals in a range of contact professions. The aggregate effect, calculated on the basis of...

Abstract

Background

Cannabis use has repeatedly been associated with psychotic symptoms, with persistent risks beyond the direct effects of exogenous cannabinoids. However, it remains unknown whether cannabis use during pregnancy is a...

Abstract

Background: Substance use is known to be episodic, dynamic, complex, and highly influenced by the environment, therefore a situational and momentary focus to alcohol craving research is appropriate. Current advances in mobile and...

Background and Aims: Childhood trauma is associated with increased levels of anxiety later in life, an increased risk for the development of substance use disorders, and neurodevelopmental abnormalities in the amygdala and frontostriatal...

ABSTRACT

Objectives: This study focused on lapse shortly after an attempt to quit smoking. Ecological momentary assessment (EMA) studies have mapped real-time situational factors that induce lapses in everyday life. However, the possible...

Abstract

Previous randomised placebo-controlled trials with low-to-medium doses of baclofen (30–60 mg) showed inconsistent results, but case studies suggested a dose-response effect and positive outcomes in patients on high doses of...