Drug overdose deaths in the United States have continued to increase at an alarming rate. The Substance Abuse and Mental Health Services Administration (SAMHSA) distributed more than $7 billion between January 2016 and...
Importance Despite the legalization and widespread use of cannabis products for a variety of medical concerns in the US, there is not yet a strong clinical literature to support such use. The risks and benefits of obtaining a...
Importance Alcohol use disorder (AUD) is common and associated with increased morbidity. The degree to which AUD currently factors into workplace absenteeism needs further characterization in the US.
Objective To examine the...
Importance Understanding mental health and substance use treatment seeking and suicidality among suicide decedents is important to determine prevention efforts.
Objective To evaluate differences in treatment seeking and...
Medication treatment for opioid use disorder (OUD) (MOUD; buprenorphine and methadone) reduces opioid use and overdose. Discontinuation of MOUD can quickly lead to relapse, overdose and death. Few persons who initiate...
Abstract
Importance The concurrent use of both tobacco and alcohol causes substantial disease and early mortality, and smokers who drink heavily tend to be less successful in smoking cessation than smokers who do not. Although varenicline...
It has been a long-standing debate in the research and medical societies whether alcohol consumption is linked to the risk of prostate cancer (PCa). Many comprehensive studies from different geographical areas and nationalities...
Mental health encompasses a range of mental, emotional, social, and behavioral functioning and occurs along a continuum from good to poor. Previous research has documented that mental health among children and adolescents is...
Importance Suicide is the second leading cause of death among youths worldwide, but no available means exist to identify the risk of suicide in this population.
Objective To assess whether genome-wide polygenic scores for...
Importance Some selective serotonin reuptake inhibitors (SSRIs) inhibit the enzymes responsible for the metabolism of oxycodone, a potent prescription opioid. The clinical consequences of this interaction on the risk of opioid...
The Ohio Attorney General selected experts from a number of academic fields to the Scientific Committee on Opioid Prevention and Education (SCOPE) to help the State of Ohio in tackling the opioid crisis in the United States. The focus of...
Abstract
Importance The rate of suicide among adolescents is rising in the US, yet many adolescents at risk are unidentified and receive no mental health services.
Objective To develop and independently validate a novel computerized...
PURPOSE: The purpose of this review is to discuss the literature regarding the concurrent use (co-use) of alcohol and cannabis and competing hypotheses as to whether cannabis acts as a substitute for (i.e., replacing the effects...
Importance Alcohol withdrawal syndrome (AWS) is a common inpatient diagnosis managed primarily with benzodiazepines. Concerns about the adverse effects associated with benzodiazepines have spurred interest in using benzodiazepine...
Source:
The ASAM Criteria® Assessment Interview Guide is the first...
Objective To assess the effectiveness of e-cigarettes in smoking cessation in the USA from 2017 to 2019, given the 2017 increase in high nicotine e-cigarette sales.
Methods In 2017, the PATH Cohort Study included data on 3578...
PURPOSE: A growing body of evidence has implicated the endocannabinoid (eCB) system in the acute, chronic, and withdrawal effects of alcohol/ethanol on synaptic function. These eCB-mediated synaptic effects may contribute to the...
Objective: The purpose of this study was to describe marketing violations from the cannabis industry in Washington State.
Method: The study team obtained records of all Washington State cannabis marketing violations from October...
Уытқұмарлықтың бұзылуы, депрессия және мазасыздану АҚТҚ -мен ауыратын адамдарға пропорционалды емес әсер етеді және сырқаттанушылық пен өлім-жітімнің артуына әкеледі. Жоспарлы скрининг осы проблемаларды шешуге көмектеседі...
