A Double Blind, Placebo Controlled Trial of Modafinil for the Treatment of Cocaine Dependence without Co-Morbid Alcohol Dependence

Like methadone for heroin dependence, modafinil is an oral medication with similar effects to cocaine but milder, slower in onset and longer-acting - properties which might help plug the gap in effective pharmacotherapies for dependence on cocaine/crack. This trial found it promoted abstinence from cocaine, but others have not, and side effects are a concern.