Trials challenge the need for the widely accepted policy of making opioid-dependent patients take their methadone or other opioid substitutes at the clinic or pharmacy, but ‘no difference’ findings may be due to the limitations of the...
Objectives: Illicit drug abuse has reached an epidemic level in the United States. Drug overdose has become the leading cause of injury-related deaths since 2008 due to the recent surge of opioid overdose by heroin, controlled...
In drug addiction, cues previously associated with drug use can produce craving and frequently trigger the resumption of drug taking in individuals vulnerable to relapse. Environmental stimuli associated with drugs or natural reinforcers...
Background: Childhood trauma affects neurodevelopment and promotes vulnerability to impaired constraint, depression, and addiction. Reduced gray matter concentration (GMC) in the mesocorticolimbic regions implicated in reward processing and...
Sigma σ1 and σ2 receptors are targets of cocaine. Despite sharing a similar name, the two receptors are structurally unrelated and their physiological role is unknown. Cocaine increases the level of dopamine, a key neurotransmitter in CNS...
Epilepsy is a devastating disease, with cognitive and emotional consequences that are not curable. In recent years, it became apparent that cannabinoids help patients to cope with epilepsy. We have studied the effects of cannabidiol (CBD)...
Introduction: Descriptive data about co-occurrence of alcohol and cocaine consumption is scarce, despite its important prevalence. Dual disorders show high prevalence in clinical samples, and patients report worse evolution and...
Researchers from the University of Sheffield have investigated UK drinker's decision making. This research examines public knowledge and use of UK drinking guidelines exploring a representative sample of the English population.
Published...
Extensive 3′ alternative splicing of the mu opioid receptor gene OPRM1 creates multiple C-terminal splice variants. However, their behavioral relevance remains unknown. The present study generated 3 mutant mouse models with...
Given the necessity to better understand the process patients need to go through in order to seek treatment via medical marijuana, this study investigates this process to better understand this phenomenon. Specifically...
To discuss the knowledge gained and future implications for incarcerated parents and community members through the development and implementation of a standardized health education and promotion module for incarcerated mothers...
Substance use is a major cause of disability globally. This has been recognized in the recent United Nations Sustainable Development Goals (SDGs), in which treatment coverage for substance use disorders is identified as one of...
Alcohol consumption pattern in India varies remarkably from many other countries. In India, most men are abstainers (70% to 90%) while less than 2% of women use alcohol. However, the men who use alcohol tend to drink at...
Background: Information technology in health sciences could be a screening tool of great potential and has been shown to be effective in identifying single-drug users at risk. Although there are many published tests for single...
This descriptive study identified latent classes of longitudinal marijuana use from ages 18 through 50 among a national sample; examined covariate associations with class membership regarding use/non-use, use intensity, and...
Objective: Analyze short- and long-term elasticities of demand for cigarettes in El Salvador as a tool for supporting recommendations on tax increases to reduce prevalence and consumption through price increases.
Methods: Demand for...
Aim: Analyze the elasticities of demand in the short and long term for cigarettes in El Salvador as a tool to support the recommendations on tax increases to reduce the prevalence and consumption by increasing prices.
Methods: Analyzed...
Aims: To investigate the impact of unit and calorie information on drinking behaviour in an ad libitum taste test paradigm.
Methods: In this experimental human laboratory study, participants were randomized to one of four...
What is already known about this topic?
Electronic cigarettes (e-cigarettes) were the most commonly used tobacco product among U.S. middle school and high school students in 2016. The Surgeon General concluded that e...
The so-called “herbal highs” are substances derived from natural plants with effects on the central nervous system. Lisergamide, ergine or LSA is the basis of different types of drugs, which are in seeds of Ipomoea...
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