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New psychoactive substances: A review and updates
New psychoactive substances (NPS) are a diverse group of substances that are linked with a number of health and social harms on an individual and societal level. NPS toxicity and dependence syndromes are recognised in primary care...
The Hidden Costs of Big Tobacco
The devastating impact of tobacco on the health of users is well known. In addition to the negative effects for the individual, there are significant economic and environmental consequences, which need to be considered when developing...
Bupropion and Naltrexone in Methamphetamine Use Disorder
Abstract
Background
The use of naltrexone plus bupropion to treat methamphetamine use disorder has not been well studied.
Methods
We conducted this multisite, double-blind, two-stage, placebo-controlled trial with the use of a...
Characterising smoking and smoking cessation attempts by risk of alcohol dependence: A representative, cross-sectional study of adults in England between 2014-2021
Summary
Background
There is a strong shared association between smoking tobacco and drinking alcohol. This study aimed to compare smoking prevalence and smoking characteristics in drinkers who were versus were not at risk of alcohol...
Trends in Cannabis Polysubstance Use During Early Pregnancy Among Patients in a Large Health Care System in Northern California
Abstract
Importance Rates of prenatal cannabis use are increasing alongside perceptions that cannabis is a harmless therapeutic for pregnancy-related ailments, while rates of prenatal use of alcohol and tobacco are decreasing. It is...
Impaired control in heavy drinking and its association with alcohol craving and alcohol use disorder severity
Abstract:
Introduction. Impaired control over drinking has been frequently cited in diverse theoretical descriptions regarding harmful alcohol use and is considered a DSM criterion for alcohol use disorder. Differences in the frequency of...
The influence of poly-drug use patterns on the association between opioid agonist treatment engagement and injecting initiation assistance
Abstract
Background
Evidence suggests people who inject drugs (PWID) prescribed opioid agonist treatment (OAT) are less likely to provide injection drug use (IDU) initiation assistance. We investigated the association between OAT...
Variations in national availability of waivered buprenorphine prescribers by racial and ethnic composition of zip codes
Background
Opioid overdose remains a public health crisis in diverse communities. Between 2019 and 2020, there was an almost 40% increase in drug fatalities primarily due to opioid analogues of both stimulants and opioids. Medications for...
Patient perspectives on depot buprenorphine treatment for opioid addiction – a qualitative interview study
Background
Recently developed buprenorphine depot injections have the potential to reduce risk for diversion and misuse, and to increase adherence with fewer visits for supervised intake. However, it is unclear how patients perceive this...
A qualitative study exploring how young people perceive and experience substance use services in British Columbia, Canada
Background
Substance use among youth (ages 12–24) is troublesome given the increasing risk of harms associated. Even more so, substance use services are largely under utilised among youth, most only accessing support when in crisis. Few...
Real-world effectiveness of pharmacological treatments of opioid use disorder in a national cohort
Abstract
Aim
To investigate the real-world effectiveness of pharmacological treatments (buprenorphine, methadone) of opioid use disorder (OUD).
Design
A nation-wide, register-based cohort study.
Setting
Sweden.
Participants
All...
Toward a Theory of Motivational Interviewing
Abstract
The widely-disseminated clinical method of motivational interviewing (MI) arose through a convergence of science and practice. Beyond a large base of clinical trials, advances have been made toward “looking under the hood” of MI...
Motivational interviewing for substance abuse
Motivational interviewing (MI) is a client‐centred, semi‐directive method for enhancing intrinsic motivation to change by exploring and resolving ambivalence. The intervention is used widely, and therefore it is important to find out...
Changes in Alcohol Use in Denmark during the COVID-19 Pandemic
Abstract
Introduction: The year 2020 was marked by the COVID-19 pandemic. Policy responses to COVID-19 affected social and economic life and the availability of alcohol. Previous research has shown an overall small decrease in alcohol use...
Building resilience in survivors of sexual exploitation: The role of children in activities implemented by NGOs in Uganda
Abstract
Children are increasingly affected by sexual exploitation (SEC), and the subsequent hardships arising out threaten their lives. Resilience is the process of adapting well in the face of trauma or other significant sources of...
Associations of common mental disorder with alcohol use in the adult general population
Abstract
Background and Aims
Research has shown that alcohol use and common mental disorders co-occur; however, little is known about how the global prevalence of alcohol use compares across different common mental disorders. The aim of...
Birth Outcomes of Neonates Exposed to Marijuana in Utero A Systematic Review and Meta-analysis
Abstract
Importance While some studies have found an association between marijuana use and adverse neonatal outcomes, results have not been consistent across all trials.
Objective To assess available data on neonatal outcomes in...
Intentions and Attempts to Quit Smoking Among Sexual Minoritized Adult Smokers After Exposure to the Tips From Former Smokers Campaign
Abstract
Importance Significant disparities exist in smoking behaviors by sexual minority status in the US.
Objective To examine potential differences in the associations between exposure to the Tips From Former Smokers (Tips) campaign...
Implementing Adolescent SBIRT
Screening, Brief Intervention, and Referral to Treatment (SBIRT) is an evidence-based approach to early intervention of substance use.
This mixed-methods evaluation assessed the implementation of an adolescent SBIRT change package across...
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