meta-analysis

Reported Theory Use by Digital Interventions for Hazardous and Harmful Alcohol Consumption, and Association with Effectiveness

Scientific article

28 February 2018

ABSTRACT Background: Applying theory to the design and evaluation of interventions is likely to increase effectiveness and improve the evidence base from which future interventions are developed, though few interventions report this...

Is Smoking a Risk Factor for Tinnitus? A Systematic Review, Meta-Analysis and Estimation of the Population Attributable Risk in Germany

Scientific article

22 February 2018

Abstract Objective: To assess the epidemiological association of smoking status and tinnitus with a systematic review and meta-analysis and to estimate the population attributable risk in Germany. Data sources: A systematic literature...

Supervised Dosing with a Long-Acting Opioid Medication in the Management of Opioid Dependence

Scientific article

20 June 2017

Trials challenge the need for the widely accepted policy of making opioid-dependent patients take their methadone or other opioid substitutes at the clinic or pharmacy, but ‘no difference’ findings may be due to the limitations of the...

Low Cigarette Consumption and Risk of Coronary Heart Disease and Stroke

Scientific article

Abstract Objective: To use the relation between cigarette consumption and cardiovascular disease to quantify the risk of coronary heart disease and stroke for light smoking (one to five cigarettes/day). Design: Systematic review and meta...

No Clear Role for Medications in Less Dependent Drinkers

Scientific article

8 December 2017

In 2013 nalmefene was authorised for moderating drinking among patients not in need of detoxification, extending pharmacotherapy to less dependent drinkers. Though uniquely authorised for this purpose, this review found other (and probably...

Mortality Risk During and After Opioid Substitution Treatment

Scientific article

17 March 2017

ABSTRACT Objective To compare the risk for all cause and overdose mortality in people with opioid dependence during and after substitution treatment with methadone or buprenorphine and to characterise trends in risk of mortality after...

The Comparative Effectiveness of Outpatient Treatment for Adolescent Substance Abuse: A Meta-Analysis

Scientific article

1 January 2013

Multi-prong therapies centred on the family emerge as probably the most effective in this comprehensive and careful synthesis of the results of trials of non-residential programmes for substance using teenagers - but do the outcomes warrant...

Does AA Really Help Drinkers Stop?

Scientific article

28 February 2017

12-step fellowships offer a way to reconcile shrunken resources with the desire to get more patients safely out of treatment. Accounting for the self-selection bias which has obscured AA’s impacts, this synthesis of US trials finds that...