methamphetamine dependence

Oxytocin as an adolescent treatment for methamphetamine addiction after early life stress in male and female rats

Scientific article

17 May 2022

Abstract Early life stress (ELS) is associated with perturbed neural development and augmented vulnerability to mental health disorders, including addiction. How ELS changes the brain to increase addiction risk is poorly understood, and...

Combination Medication Therapy for Methamphetamine Use Disorder

Scientific article

14 January 2021

A combination therapy of injectable naltrexone and oral bupropion was found in a randomized clinical trial to improve outcomes for patients with methamphetamine use disorder. This is important because there are no widely approved medication...

Identification of Novel Signal Transduction, Immune Function, and Oxidative Stress Genes and Pathways by Topiramate for Treatment of Methamphetamine Dependence Based on Secondary Outcomes

Scientific article

13 December 2017

Background: Topiramate (TPM) is suggested to be a promising medication for treatment of methamphetamine (METH) dependence, but the molecular basis remains to be elucidated. Methods: Among 140 METH-dependent participants randomly assigned to...