Causal relationships between substance use and insomnia

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Source:

Pasman, J., Smit, D., Kingma, L., Vink, J., Treur, J., & Verweij, K. (2020, July 02). Causal relationships between substance use and insomnia. Retrieved from https://www.sciencedirect.com/science/article/pii/S0376871620303161

Highlights

•Insomnia and substance use have been linked, but the causal direction is unclear.
•With Mendelian Randomization causal relationships can be tested using genetic data.
•Insomnia causes smoking, alcohol dependence, and cannabis initiation.
•Smoking initiation (not alcohol use/dependence or cannabis initiation) causes insomnia.

Causal relationships between substance use and insomnia_0.pdf

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