Treatment

Abstract Objectives: Investigate the acceptability of financial incentives for initiating a medically supervised benzodiazepine discontinuation programme among people with long-term benzodiazepine use and to identify programme features that...

Explores how harm reduction impacts are affected by the management of the service and of the intervention. Highlights the studies which showed that treatment-termination and needle-exchange policies can mean life or death for service users...

Abstract The aim of the study was to examine the effects of a brief stage-matched smoking cessation intervention group compared with a control group (with usual care) in type 2 diabetes mellitus patients who smoked by randomized controlled...

ABSTRACT Background: Treatment of alcohol use disorders (AUDs) is characterized by an adherence rate below 50%. Clinical research has found that patient adherence enhances treatment effect; hence, health authorities, clinicians, and...

Abstract Recent animal studies demonstrate that compulsive cocaine seeking strongly reduces prelimbic frontal cortex activity, while optogenetic stimulation of this brain area significantly inhibits compulsive cocaine seeking, providing a...

Abstract Previous randomised placebo-controlled trials with low-to-medium doses of baclofen (30–60 mg) showed inconsistent results, but case studies suggested a dose-response effect and positive outcomes in patients on high doses of...

Second cell of the Drug Treatment Matrix explores key studies on the impact of the practitioner on reducing harms associated with illegal drug use, in which trust emerges as a fundamental ingredient. Reconceptualise needle exchanges as safe...