پس منظر اوپیوئڈز اور سکون آور ادویات عام طور پر دائمی رکاوٹ پھیپھڑوں کی بیماری (سی او پی ڈی) کے مریضوں میں ڈسپنیا ، درد ، بے خوابی ، افسردگی اور اضطراب کی علامات کے لئے تجویز کی جاتی ہیں۔ عمر رسیدہ افراد کو مشورہ دیا جاتا ہے کہ وہ...
Cocaine addiction is a significant medical and public concern. Despite decades of research effort, development of pharmacotherapy for cocaine use disorder remains largely unsuccessful. This may be partially due to insufficient...
Abstract
Background
The use of naltrexone plus bupropion to treat methamphetamine use disorder has not been well studied.
Methods
We conducted this multisite, double-blind, two-stage, placebo-controlled trial with the use of a...
Importance Rates of prenatal cannabis use are increasing alongside perceptions that cannabis is a harmless therapeutic for pregnancy-related ailments, while rates of prenatal use of alcohol and tobacco are decreasing. It is...
اخذ کرنا
مینتھول سگریٹ کے دھوئیں کو کم نقصان دہ بنا سکتا ہے اور نوجوانوں کو زیادہ بار تمباکو نوشی کرنے اور نکوٹین پر زیادہ انحصار کرنے کا باعث بن سکتا ہے۔
مقصد نوجوان سگریٹ استعمال کرنے والوں میں سگریٹ نوشی کی فریکوئنسی اور نکوٹین پر...
The opioid crisis is a major public health challenge in the United States, killing about 70,000 people in 2020 alone. Long delays and feedbacks between policy actions and their effects on drug-use behavior create dynamic...
Importance Patients who use cannabis for medical reasons may benefit from discussions with clinicians about health risks of cannabis and evidence-based treatment alternatives. However, little is known about the prevalence of...
Importance Nonnicotine e-cigarettes contain chemicals, flavorants, and solvents that have known health harms and/or have not been proven safe for inhalation.
Objective To evaluate nonnicotine e-cigarette use patterns, including...
Opioid overdose remains a public health crisis in diverse communities. Between 2019 and 2020, there was an almost 40% increase in drug fatalities primarily due to opioid analogues of both stimulants and opioids. Medications for...
Importance Alcohol-associated liver disease (ALD) is one of the most devastating complications of alcohol use disorder (AUD), an increasingly prevalent condition. Medical addiction therapy for AUD may play a role in protecting...
Smoking is the leading cause of preventable illness in the world today. Prenatal cigarette smoke exposure (PCSE) is a particularly insidious form because so many of its associated health effects befall the unborn child and produce...
Importance Significant disparities exist in smoking behaviors by sexual minority status in the US.
Objective To examine potential differences in the associations between exposure to the Tips From Former Smokers (Tips) campaign...
BACKGROUND: Alcohol and marijuana are commonly used by young adults, and use of both substances, particularly at the same time, is prevalent among this population. Understanding the prevalence, patterns, correlates, and...
To assess the impact of fetal exposure to cannabis on adiposity and glucose-insulin traits in early life.
We leveraged a subsample of 103 mother-child pairs from Healthy Start, an...
In the context of the current U.S. injection drug use epidemic, targeted public health harm reduction strategies have traditionally focused on overdose prevention and reducing transmission of blood-borne viral...
Increasing buprenorphine/naloxone (B/N) access for opioid use disorder (OUD) is essential yet ensuring adherence and preventing diversion remains challenging. This study examines the feasibility, usability, and...
Importance Psychiatric disorders may be associated with an increased risk for SARS-CoV-2 breakthrough infection after vaccination, but no studies have tested this hypothesis.
Objective To evaluate whether past diagnoses of...
Drug overdose deaths in the United States have continued to increase at an alarming rate. The Substance Abuse and Mental Health Services Administration (SAMHSA) distributed more than $7 billion between January 2016 and...
Importance Despite the legalization and widespread use of cannabis products for a variety of medical concerns in the US, there is not yet a strong clinical literature to support such use. The risks and benefits of obtaining a...
Importance Alcohol use disorder (AUD) is common and associated with increased morbidity. The degree to which AUD currently factors into workplace absenteeism needs further characterization in the US.
Objective To examine the...
