Glioblastoma (GBM) is the most malignant brain tumor and one of the deadliest
types of solid cancer overall. Despite aggressive therapeutic approaches consisting of
maximum safe surgical resection and radio-chemotherapy, more than 95% of...
Abuse-deterrent opioid formulations have been suggested as one way to decrease the abuse, addiction, and overdose of orally prescribed opioids. Ten oral opioid formulations have received abuse-deterrent labeling by the U.S. Food...
Background: Alcoholic cardiomyopathy (ACM) is defined by a dilated and impaired left ventricle due to chronic excess alcohol consumption. It is largely unknown which factors determine cardiac toxicity on exposure to alcohol.
...A study published in the LGBT Health Journal explores family rejection as a predictor for substance misuse in transgender and gender nonconforming adults.
Taking data from the National Transgender Discrimination Survey the study...
This article examines the effect of exposure to criminal violence on fear of crime and mental health in Mexico, a country that has experienced a dramatic rise in violent events resulting from the operation of drug trafficking...
Background: Alcohol misuse is a major social and public health issue in Australia, with an estimated cost to the community of Aus $30 billion per annum. Until recently, a major barrier in addressing this significant public...
Like methadone for heroin dependence, modafinil is an oral medication with similar effects to cocaine but milder, slower in onset and longer-acting - properties which might help plug the gap in effective pharmacotherapies for dependence on...
Objectives: Secondhand smoke (SHS) exposure is associated with cardiovascular disease. This study aims to determine the association between SHS exposure estimated by questionnaire and hypertension in Korean never smokers.
Set...
Objectives: This study aimed to develop and validate an online instrument to: (1) identify common alcohol-related social influences, norms and beliefs among adolescents; (2) clarify the process and pathways through which...
A study exploring the completion of outpatient substance use disorder treatment has highlighted racial and ethnic health disparities.
The research team utilised a sample of 416,224 outpatient discharges in the study which found people...
Policy interventions such as public health mass media campaigns disseminate messages in order to improve health-related knowledge, attitudes, beliefs and behaviors at the population level. Only more recently have campaigns that...
Aerosol composition measurements made in an indoor classroom indicate the uptake of thirdhand smoke (THS) species to indoor particles, a novel exposure route for THS to humans indoors. Chemical speciation of the organic aerosol...
To examine changes in hospital workers’ interventions before and after online training.
Pre-post evaluation of the self-reported performance of the 5A's by hospital workers from the three organizations...
Background: Structural imaging studies of cannabis users have found evidence of both cortical and subcortical volume reductions, especially in cannabinoid receptor-rich regions such as the hippocampus and amygdala. However, the findings...
Tobacco addiction is a complex, multicomponent phenomenon stemming from nicotine’s pharmacology and the user’s biology, psychology, sociology, and environment. After decades of public denial, the tobacco industry...
Opioid-related overdose deaths have risen sharply among young adults. Despite this increase, access to evidence-based medication for opioid agonist treatment (OAT) for youth remains low. Among older adults...
Overview
Alcohol use disorders are alarmingly high in the University population. Screening instruments is essential for the measurement of the epidemiological and clinical practice. The objective of this study is to compare the...
Novel molecular targets are needed to develop new medications for the treatment of cocaine addiction. Here we investigated a role for glucagon-like peptide-1 (GLP-1) receptors in the reinstatement of cocaine-seeking behavior, an...
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