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Trends in healthcare expenditures and resource utilization among a nationally representative population with opioids in the United States: a serial cross-sectional study, 2008 to 2017
One of the most serious public health concerns in recent decades has been the opioid epidemic in the United States (US). Over 9.9 million Americans aged 12 and up abused prescription pain drugs in 2018, and roughly 2 million Americans were...
Assessing the Prevalence of Fetal Alcohol Spectrum Disorder (FASD) in the UK
In a new study, led by a team at the University of Salford, evidence has been found to suggest fetal alcohol spectrum disorder (FASD) is a significant issue among the population, likely to be as common as autism, despite being rarely...
Research led by people who use drugs: centering the expertise of lived experience
Despite a long history of successful, community-led harm reduction programs and rising health inequalities suffered by PWUD, research collaborations between PWUD and researchers remain generally ignored. PWUDs are crucial in identifying...
Psychosocial Interventions to Improve Psychological, Social and Physical Wellbeing in Family Members Affected by an Adult Relative’s Substance Use: A Systematic Search and Review of the Evidence
The use of alcohol and drugs is a significant public health concern and is prevalent in families. Over 100 million people are thought to be affected by a close relative's substance use, with many experiencing negative health and social...
Addictive behaviors and craving during the COVID-19 pandemic of people who have recovered from substance use disorder
Harm reduction drug policy in Israel: what has been accomplished and what still needs to be done?
Evaluation of neurotrophic factors and education level as predictors of cognitive decline in alcohol use disorder
Abstract
Cognitive reserve (CR) is the capability of an individual to cope with a brain pathology through compensatory mechanisms developed through cognitive stimulation by mental and physical activity. Recently, it has been suggested that...
Periods of altered risk for non-fatal drug overdose
The risk of an individual overdosing is influenced by a range of, often overlapping circumstances. Factors such as incarceration, mental and physical health conditions, and the treatments prescribed for these conditions can all affect the...
Reprint of: Biotechnologies and the future of opioid addiction treatments
Biotechnological treatment, including addiction treatment, is the way of the future. Researchers and pharmaceutical companies praise depot injections, agonist/antagonist implants, deep brain stimulation, and hapten conjugate vaccines as...
Identifying content-based engagement patterns in a smoking cessation website and associations with user characteristics and cessation outcomes: a sequence and cluster analysis
Tobacco smoking is the greatest cause of sickness and early death worldwide, with 8 million people dying each year from a smoking-related condition. The use of pharmaceutical or behavioural assistance improves smokers' chances of quitting...
The link between reducing pain medication, overdose and mental health crisis
In response to the concerning numbers of opioid-related deaths in the US, there has been a recent focus on opioid prescribing trends, which has shown an increase in opioid tapering among patients prescribed long-term opioid therapy. However...
The impact of COVID-19 on drug use and harm reduction programming in the Middle East and North Africa (MENA) region: a regional consultation of stakeholders and people who use drugs
COVID-19 (SARS-CoV-2) was classified a pandemic on March 11, 2020, with early reports of the disease occurring in the Middle East and North African (MENA) area. On January 2021, the World Health Organization Eastern Mediterranean Regional...
Addressing long overdue social and structural determinants of the opioid overdose crisis: Drug and Alcohol Dependence Special Issue
This special issue addresses a rapidly growing area of research with a pressing public health need, the social structure of opioid use.
Specifically, this issue compiles original articles that apply theoretical and empirical frameworks to...
Urdu translation and adaptation of the HIV stigma scale in Pakistani injectable drug users with HIV
Abstract
Objective: To translate and adapt the human immunodeficiency virus stigma scale into Urdu language,
and to determine its psychometric properties.
Method: The study was conducted at the Human Immunodeficiency Virus / Acquired...
Gender disparities in opioid treatment progress in methadone versus counselling
The high dropout rate (75%) in opioid use disorder (OUD) treatment among women and racial/ethnic minorities in the United States necessitates a better knowledge of the factors that contribute to treatment success. While therapy and...
High-dose buprenorphine induction in the emergency department for treatment of opioid use disorder
In response to the rising efficacy of the illicit opioid drug supply and often observed delays in access to follow-up therapy, emergency departments (EDs) occasionally utilize a high-dose buprenorphine induction method for the treatment of...
Biochemical mechanisms associating alcohol use disorders with cancers
Abstract
The World Health Organization identifies alcohol as a cause of several neoplasias of the oropharynx cavity, esophagus, gastrointestinal tract, larynx, liver, or female breast. We review ethanol’s nonoxidative and oxidative...
Variation in brief treatment for substance use disorder: a qualitative investigation of four federally qualified health centres with SBIRT services
Brief treatment (BT) or regular outpatient alcohol use or substance use disorder (SUD) treatment is a key element of the Screening, Brief Intervention, and Referral to Treatment (SBIRT) model. It can be an effective, short-term, and low...
The relationship between early childhood trauma and the rewarding effects of morphine
Research from the University of Exeter has highlighted how childhood trauma can make individuals more sensitive to the pleasurable and motivational effects of opioids and less sensitive to the negative consequence of the drugs.
The...
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