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Abuse-Deterrent Opioid Formulations
Abstract
Abuse-deterrent opioid formulations have been suggested as one way to decrease the abuse, addiction, and overdose of orally prescribed opioids. Ten oral opioid formulations have received abuse-deterrent labeling by the U.S. Food...
Genetic Etiology for Alcohol-Induced Cardiac Toxicity
Abstract
Background: Alcoholic cardiomyopathy (ACM) is defined by a dilated and impaired left ventricle due to chronic excess alcohol consumption. It is largely unknown which factors determine cardiac toxicity on exposure to alcohol.
Obje...
Family Rejection as a Predictor of Suicide Attempts and Substance Misuse among Transgender and Gender Nonconforming Adults
A study published in the LGBT Health Journal explores family rejection as a predictor for substance misuse in transgender and gender nonconforming adults.
Taking data from the National Transgender Discrimination Survey the study involved...
A Double Blind, Placebo Controlled Trial of Modafinil for the Treatment of Cocaine Dependence without Co-Morbid Alcohol Dependence
Like methadone for heroin dependence, modafinil is an oral medication with similar effects to cocaine but milder, slower in onset and longer-acting - properties which might help plug the gap in effective pharmacotherapies for dependence on...
Racial & Ethnic Disparities in Outpatient Treatment Completion
A study exploring the completion of outpatient substance use disorder treatment has highlighted racial and ethnic health disparities.
The research team utilised a sample of 416,224 outpatient discharges in the study which found people of...
Larger Gray Matter Volume in the Basal Ganglia of Heavy Cannabis Users Detected by Voxel-Based Morphometry and Subcortical Volumetric Analysis
Background: Structural imaging studies of cannabis users have found evidence of both cortical and subcortical volume reductions, especially in cannabinoid receptor-rich regions such as the hippocampus and amygdala. However, the findings...
Características de los Instrumentos de Tamizaje del Trastorno por Uso de Alcohol en Jóvenes Universitarios de Argentina
Resumen
Los trastornos por uso de alcohol son preocupantemente altos en la población universitaria. Contar con instrumentos de tamizaje es fundamental para la medición epidemiológica y la práctica clínica. El objetivo de este trabajo es...
Glucagon-Like Peptide-1 Receptor Activation in the Ventral Tegmental Area Attenuates Cocaine Seeking in Rats
Abstract
Novel molecular targets are needed to develop new medications for the treatment of cocaine addiction. Here we investigated a role for glucagon-like peptide-1 (GLP-1) receptors in the reinstatement of cocaine-seeking behavior, an...
Twelve Million Smokers Look Online for Smoking Cessation Help Annually
Abstract
Background
This study quantified the potential reach of Internet smoking cessation interventions to support calculations of potential population impact (reach × effectiveness). Using a nationally representative survey, we...
First and Subsequent Lifetime Alcoholism and Mental Disorders in Suicide Victims with Reference to a Community Sample
Background: Suicide victims have been found to frequently suffer from mental disorders, often more than one, and comorbidity has also been found to be a risk factor for suicide. The aim of the present study was to determine the first...
Psychological and Psychosocial Interventions for Cannabis Cessation in Adults
Abstract
Objective: Many psychological and psychosocial interventions have been developed to treat regular users of cannabis, but it is unclear which intervention(s) are the most effective. This article aims to assess the effectiveness of...
Medical Marijuana Users Are More Likely to Use Prescription Drugs Medically and Nonmedically
ABSTRACT
Objectives: Previous studies have found a negative population-level correlation between medical marijuana availability in US states, and trends in medical and nonmedical prescription drug use. These studies have been interpreted...
The Influence of Psychological Factors during Early Years of Life in the Development of Addiction
Abstract
Addiction is a multifaceted condition with various entry and exit points throughout its course in an individual's life. In some adolescents, early onset can be followed by limited adolescent use or abuse and is more related to...
آب نبات و سایر ترکیب ها: شناسایی ترکیب مواد مخدر و مواد مخدر از انجمن آنلاین
مواد روانگردان جدید (NPS) به ترکیب های مصنوعی یا مشتقات مواد سوء استفاده که به طور گسترده ای شناخته شده تر است که در طول دو دهه گذشته پدیدار شده است اشاره دارد. گزارش های موردی حاکی از آن است که کاربران موادی را با هم ترکیب می کنند تا به...
گسترش بيماری های دندانی و دندانی و بهداشت دندان در سوء مصرف کنندگان مواد مخدر
آبستره
سابقه و هدف: در میان افراد متعلق به گروه های مختلف جامعه، به ویژه در میان جوانان در بنگله دیش و همچنین در کشورهای غربی، اعتیاد به برخی مواد مخدر غیرقانونی افزایش یافته است. سوء مصرف مواد مخدر منجر به عواقب مستقیم متعددی از جمله...
اندازه گیری بار مرگ و میر ناشی از مواد مخدر در انتاریو کانادا
مصرف بیش از حد مواد مخدر یک مشکل پیشرو در بهداشت عمومی در سراسر کانادا است که همچنان در حال تکامل است، به ویژه به عنوان مواد مخدر مخفیانه تولید وارد بازار (آژانس بهداشت عمومی کانادا، 2017). در سال 2014، ما یک مطالعه منتشر شده است که نشان...
Addiction, 12-Step Programs, and Evidentiary Standards for Ethically and Clinically Sound Treatment Recommendations: What Should Clinicians Do?
Abstract
Addiction is a complex phenomenon characterized by a loss of control and compulsive, habitual behavior. Since there is no single, specific cause for addiction, there is no single, standard treatment for it. A variety of approaches...
اصلاح حاد و مزمن پلاستیک اندوکانابینوید ‐ توسط نیکوتین
آبستره
سیستم اندوکانابینوید (eCB) چندین پدیده مربوط به رفتارهای اعتیاد آور را اصلاح می کند، و تغییرات ناشی از مواد مخدر‐ در سیگنالینگ eCB به عنوان میانجی های مهم پاداش فیزیولوژیکی و پاتولوژیک‐ پلاستیتیک سیناپسی مرتبط با آن، بیان شده است...
درمان مبتنی بر تمرکز حواس اعتیاد: وضعیت فعلی این زمینه و پیش بینی موج بعدی تحقیقات
آبستره
پیشرفت های معاصر در علوم اعصاب اعتیاد به موازات افزایش علاقه به عمل آموزش ذهنی باستانی مراقبه تمرکز حواس به عنوان یک درمان بالقوه برای اعتیاد. در دهه گذشته، مداخلات مبتنی بر تمرکز حواس (MBIs) به عنوان یک درمان برای یک آرایه رفتارهای...
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