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Highlights

• The study examines the views of patients with alcohol use disorder on relapse.
• Relapse was associated with the use of alcohol as a means of self-regulation combined with the sense of being disconnected from other people.

Th...

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Substance use is one way that people deal with the difficult symptoms present in mood and anxiety disorders. As people become more reliant on the effects of the substances to relieve distress the use can develop into dependence. Self‐medica...

Abstract

Background

Substance use disorders are associated with poorer clinical outcomes in patients with schizophrenia. There is no specific treatment for amphetamine or cannabis use disorder, but methadone and buprenorphine are used...

Benzodiazepines, such as sedatives and sleeping aids, are a widely prescribed group of medicines designed for short-term treatment. Although most people manage benzodiazepines as prescribed, some individuals misuse the drugs and can develop...

Opioid medication for chronic pain can be an effective treatment. Most patients take the medication as prescribed, however some individuals can become addicted to the drug, leading to opioid misuse. Prescription opioid misuse is a...

Hepatitis C is a highly infectious blood-borne virus that affects the cells of the liver causing inflammation. Although many people with the virus may have no symptoms at all people can experience jaundice, depression, fatigue, skin...

Key Points

Question: Does a lay health worker–delivered psychological intervention improve symptoms of depression and anxiety in Zimbabwe?

Findings: In a cluster randomized clinical trial of 573 randomized patients with common mental...

Scottish Health Action on Alcohol Problems (SHAAP) has published its latest report, ‘Dying for a drink’. 

Scottish people tend to consume more alcohol than people in England and Wales. Alcohol is a harmful substance and, consumed in...

Young adults between the ages of 18 and 24 who are in college are more likely, compared to their non-college peers, to drink to excess. College drinking remains a significant public health concern with consequences including poorer academic...

The endocannabinoid system is widespread throughout the central nervous system and its type 1 receptor (CB1) plays a crucial role in preventing the neurotoxicity caused by activation of glutamate N-methyl-D-aspartate receptors (NMDARs)...

Cannabis remains the most commonly used illicit drug worldwide and, with the rise of decriminalisation and legalization of marijuana for medical and recreational use, it is expected this will increase even further. There are, however...