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Background

The long-running opioid epidemic and the more recent COVID-19 pandemic are two interrelated events with major public health implications for people who use opioids (OUD). The majority of studies on the interaction of these two...

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Importância  Apesar da legalização e do uso generalizado de produtos de cannabis para uma variedade de preocupações médicas nos EUA, ainda não há uma literatura clínica forte para apoiar esse uso. Os riscos e benefícios da...

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Importância  O transtorno por uso de álcool (AUD) é comum e está associado ao aumento da morbidade. O grau em que o AUD atualmente influencia o absenteísmo no local de trabalho precisa de uma caracterização mais aprofundada nos...

Abstract

Importance  Understanding mental health and substance use treatment seeking and suicidality among suicide decedents is important to determine prevention efforts.

Objective  To evaluate differences in treatment seeking and...

Abstract

The aim of this study was to explore the role of stigma in different diagnoses of mental illness. A cross-sectional study (N = 255) was developed in two groups: users of a rehabilitation network for people with severe mental...

Este artigo apresenta uma análise de fatores sociodemográficos e familiares relacionados ao uso de substâncias psicoativas em adolescentes do décimo ano de uma escola pública no Cantão de Montes de Oca. A abordagem foi quantitativa...

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Fundo

O tratamento medicamentoso para transtorno por uso de opioides (TOU) (MOUD; buprenorfina e metadona) reduz o uso de opioides e a overdose. A descontinuação do MOUD pode levar rapidamente a recaída, overdose e morte...

Abstract

This study examines the usefulness of two AUDIT adaptations with a sample of 907 undergraduate alcohol users. On the one hand, it includes the AR2i that encompasses revised A2r and A3r consumption items, and on the other hand—in...

Abstract

Age of onset has been reported as a crucial predictor for alcohol consumption in adolescence. However, several authors have warned against it as an unreliable artefact accounted by the tendency to delay age of onset as...

Abstract

Importance  Understanding the effects of modifiable risk factors on risk for multiple sclerosis (MS) and associated neurodegeneration is important to guide clinical counselling.

Objective  To investigate associations of...

Abstract

Importance  The concurrent use of both tobacco and alcohol causes substantial disease and early mortality, and smokers who drink heavily tend to be less successful in smoking cessation than smokers who do not. Although...

Abstract

Reduced inhibitory control and a hypersensitivity to reward are key deficits in drug dependents; however, they tend to be studied in isolation. Here, we seek to understand the neural processes underlying control over reward and...

Abstract

Our aim was to assess the cognitive and emotional state, as well as related-changes in the glucocorticoid receptor (GR), the corticotropin-releasing factor (CRF) and the brain-derived neurotrophic factor (BDNF) expression of...

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Embora tenha sido sugerido que o uso de cocaína e a recaída nas mulheres estão mais fortemente relacionados ao desejo de alívio do estresse, enquanto o uso de cocaína nos homens está mais fortemente relacionado ao desejo de...

Abstract

Although previous research in alcohol dependent populations identified alterations within local structures of the addiction ‘reward’ circuitry, there is limited research into global features of this network, especially in early...

Abstract

Binge drinking is a pattern of intermittent excessive alcohol consumption that is highly prevalent in young people. Neurocognitive dual-process models have described substance abuse and adolescence risk behaviours as the result...

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Pacientes com transtorno de déficit de atenção/hiperatividade (TDAH) geralmente desenvolvem transtorno por uso de substâncias (SUD) de início precoce e apresentam resultados ruins no tratamento. Ambos os distúrbios mostram...