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Treatment
Applying interventions designed to reduce and manage the symptoms of substance use disorders.
Cocaine Elicits Autophagic Cytotoxicity via a Nitric Oxide-GAPDH Signaling Cascade
Abstract
Cocaine exerts its behavioral stimulant effects by facilitating synaptic actions of neurotransmitters such as dopamine and serotonin. It is also neurotoxic and broadly cytotoxic, leading to overdose deaths. We demonstrate that...
New Evidence in Mice That Cocaine Makes Brain Cells Cannibalize Themselves
Working with mice, researchers at Johns Hopkins have contributed significant new evidence to support the idea that high doses of cocaine kill brain cells by triggering overactive autophagy, a process in which cells literally digest their...
ISSUP Mexico 2017
At the beginning of April ISSUP’s Deputy Executive Director, Joanna Travis-Roberts, headed to Cancún, Mexico to plan for this year’s Annual ISSUP Workshop.
EMCDDA Treatment Standards and Best Practice
Discover what works (and what doesn't work) in the areas of drug prevention, treatment and social reintegration.
Effectiveness Bank Matrix Bite: Psychosocial Therapies in the Treatment System
This is one of 25 cells in the Alcohol Treatment Matrix. The cell discusses key research relating to the roles of psychosocial therapies in local treatment systems. In particular, their role in creating a cost-effective mix of services...
Should Opioid Dependent Patients Receive Immediate Access to Medical Treatment?
New research supported by the National Institute on Drug Abuse (NIDA) has found through a comparison of treatment approaches for opioid dependence that, in an emergency setting, combining the medication buprenorphine with on-going care is...
Can Abstaining from Alcohol Help to Fight the Spread of HIV?
Studies have shown that alcohol may play a role in more that 13% of deaths resulting from infectious diseases, including HIV.
Evidence suggests that alcohol consumption negatively affects the fight against HIV primarily by:
- Increasing...
Could LSD Have a Role in New Therapeutic Treatments?
New research published in the journal Translational Psychiatry has found that LSD reduces activity in the region of the brain responsible for negative emotions such as fear.
The researchers call this the drug’s ‘de-frightening effect’...
Does Smoking Cigarettes Increase the Chance of Relapse into Illegal Substance Use?
Among people recovering from substance use disorders, those who smoke are more likely to relapse three years later compared to those who do not, according to new findings published in The Journal of Clinical Psychiatry.
Treatment for...
Organisational Influences on Psychosocial Therapies
Latest instalment of online course on alcohol treatment research. See if you agree with influential US researchers that “organizational climate underlies the entire process of innovation adoption”, appreciate the effect of high staff...
Drugs on the Brain: Substance Use and Neurotransmission
The National Institute on Drug Abuse (NIDA) has published an extended overview detailing the impact of certain drugs on brain functioning, as well as the most common experimental methods used in related research.
Neuroscientists...
Minimum Alcohol Price to Be Rolled out across the UK?
A minimum price of 50p per unit of alcohol was approved by Members of Scottish Parliament (MSPs) in 2012. The decision faced numerous legal challenges from the drinks industry before Scottish courts ruled in its favour in October 2016. This...
Tweet2Quit: The Social Media Intervention Helping People to Quit Smoking
The social media quit-smoking intervention – Tweet2Quit – sends automated daily communications to private self-help groups, encouraging high-quality peer-to-peer discussions online. It is very low cost and has a potential global reach.
A...
The Comparative Effectiveness of Outpatient Treatment for Adolescent Substance Abuse: A Meta-Analysis
Multi-prong therapies centred on the family emerge as probably the most effective in this comprehensive and careful synthesis of the results of trials of non-residential programmes for substance using teenagers - but do the outcomes warrant...
Clinical Application of Cultural Elements for Hispanic and Latino Populations
This manual is designed to teach cultural competence concepts, values, and strategies for engagement and treatment with Hispanics and Latinos with substance use disorders (SUD). The manual introduces a basic understanding of cultural...
The Growing Need to Address the Use of New Psychoactive Substances
A recent paper published in the International Journal of Drug Policy addresses the current health responses to new psychoactive substances (NPS), highlighting key issues to inform the planning and implementation of adequate responses in the...
Effectiveness Bank Matrix Bite: Managing the Talking Route to Recovery
Fortnightly instalment of online course on alcohol treatment research starts with a study which concluded that “leaders have a cascading impact on their staff in ways other than through mandate”. Findings that post-training ‘coaching’ is...
Quality of Behavioural Drug Treatment Implementation Dictates its Success
Contingency management (CM) is a widely used behavioural therapy for substance use disorders. It offers material rewards for attending sessions and adhering to prescribed medication courses, amongst other positive behaviours.
A study...
Mental Health and Synthetic Cannabinoid Use
Recently published in the journal Pediatrics, the first prospective study of synthetic cannabinoids (SCs) – chemicals that mimic the effects of marijuana – links depressive symptoms and marijuana and alcohol consumption with an increased...
A Scientific Development for the Treatment of Cocaine Addiction?
A new study published in the journal Biological Psychiatry claims that one’s desire for cocaine may be reduced by blocking signalling from a specific system in the brain primarily responsible for promoting wakefulness and appetite.
The...